Shakespeare's tragic character "Ophelia" from Hamlet is a very popular subject for artists. Besides it being probably pretty fun to paint an insane, beautiful girl who throws herself in a river to drown, most people can relate to those melodramatic feelings after being rejected. If you want to see more Ophelia paintings there are some here and here...
Ernest Hebert "Ophelia"
James Sant "Ophelia"
John Severn "Ophelia"
John William Waterhouse "Ophelia"
The Drowning of Ophelia by W.G. Simmons
This one below is not technically Ophelia, but it makes me think of her anyway...
"The Young Martyr" by Paul Delaroche